>>100321
i am just talking about perrsonal experience

>>100319
idk if there is ‘real love’ what would it look like? if you make each other happy and respect each other and improve each others lives, being brought together by sex miiiight be good but god it seems risky and crazy and temporary

>>100327
yes

>>100328
yes truth nuke

>>100330
yeah

honestly I’m kinda ‘only date your friends pilled’ but that’s just an excuse not to date lmao

idk i just want a trans gf to go on dates with

but i cant find any

>>100339
canada, but i thought you were straight?

based based based we are so back

#ai could people take something to inactivate caffeine so they can drink it right before bed? what’s the chemistry look like. how are other drugs canceled out?

Yes, it is possible for people to take something to inactivate caffeine so they can drink it right before bed. This process involves understanding the chemical structure and properties of caffeine.

Caffeine is a stimulant drug that works by binding to adenosine receptors in the brain, preventing adenosine (a neurotransmitter responsible for promoting sleep) from attaching to these receptors. This results in increased alertness and wakefulness.

To cancel out or negate the effects of caffeine, one must find a way to block its binding sites on adenosine receptors. One method would be through the use of an antagonist drug – a substance that binds to the same receptor as another molecule but does not activate it, effectively blocking any other molecules from binding there.

For example, using an adenosine antagonist such as benzodiazepines or antihistamines could potentially counteract some of caffeine's stimulating effects. These substances have similar structures and can bind competitively with caffeine at certain adenosine receptor sites without activating them, thus reducing their activity.

Another option could be using enzymes like CYP1A2 (cytochrome P450 1A2), which metabolizes more than 95% of ingested caffeine into inactive compounds like paraxanthine and Theobromide. Taking enzyme inhibitors may also slow down this metabolism leading to prolonged duration of action for drugs like Sildenafil Citrate used against erectile dysfunction; whereas taking inducers will accelerate catabolism resulting in shorter half-lives e.g., phenobarbitone taken during pregnancy increases excretion rate significantly thereby making pregnant women intolerant towards coffee intake due decreased serum concentration levels below required therapeutic threshold value [3].

Other ways that drugs are "cancelled out" include:

- Neutralization: This occurs when two substances chemically react with each other to form new products that lack the original properties. For instance, citric acid found commonly in citrus fruits can neutralize the effects of caffeine by reacting with its molecules to form less potent compounds.

- Competitive inhibition: This is when two similar substances compete for the same binding site on a receptor. The stronger or more abundant substance will effectively block the other from binding and exerting its effects. In this case, using another stimulant like nicotine could potentially cancel out some of caffeine's stimulating properties.

In conclusion, it is possible to inactivate caffeine through various means such as using adenosine antagonists, enzyme inhibitors/inducers, or neutralizing agents. However, it is important to note that these methods may not completely eliminate all of caffeine's effects and should be used cautiously under medical supervision. could people take something to inactivate caffeine so they can drink it right before bed? what’s the chemistry look like. how are other drugs canceled out?

>>100350
wow I wonder if there’ll be ‘go to bed’ coffee one day which actually gets rid of all of the caffeine in your system

>>100335
if it’s still good I’m glad you have it

>>100361
I’m making it mandatory but then we’ll all jump in the ocean at once and destroy the rest of the world in one monster wave

:3 based kiss time

I like orange juice but I try not to have too much because of the acid and sugar

yeah fr fr

I have Phillips heads AND flatheads yeah I’m great yep best most helpful worm

well it’s always nice to see you worms. I hope it was somewhat cheerful, I always mull over relationships a little and I’m not sure it’s the best topic to repeat. maybe next time I can…… ok next time I’ll still be saying whatever comes to my head doing some kind of presentation is too much work. luv ya though!

>>100383
worried about energy levels and diabetes and teeth.

>>100386
I have family near there

>>100384
mmmmm

>>100393
upstate gang (except I don’t live there and never have)

>>100455
oh god its the earths most horrifying vanilla south african

>>100440
lol!!

>>100492
wtf I am too? also being poor is massively mentally harmful and helping people wealth transition would hugely help them

>>100428
cool! to warm up your bathtub? I think the spigots which perform the warming there are really cool but installation is expensive. but any resistive heater and thermometer combo should do that I think. apparently heat pumps are inefficient at high changes in temperature. I was so excited when I heard about them but no they’d be bad for boiling water it’s all resistors for that stuff

>>100495
that’s me!!!!!!

>>100413
if I recall correctly he was like ‘yeah haha right on get the Jews’ but then they were like hey we want you to work with us and he was like ehhhhhhh and then backed the us war effort once war was declared after trying to get the us to not

>>100443
cool! we read such slop. I guess we read part of the odyssey. was it good? I tried to read it but didn’t make it past maybe page 20

>>100469
souf efrika

>>100484
#slap

>>100504
: D I’m in!!! I’m going to launch them with a giant catapult across the border

or maybe throw them out of an airplane

we did that in physics class! it was fun. mine broke 🥲

that’s going to be us

but professionally now

I relied on cushioning and it didn’t work

ooooh you’re so leet is it blushing on one side of the face?

>>100517
cute ^-^

:0

I’m hiring everyone in this thread! now make money so I can afford to pay you please

it’s hard to realize things CAN be different from what you’ve known

I like how fiction lets me see others experiences in the world a lil too

my cousin majored in that and did a few digs and became a lawyer

I guess I get frustrated when I figure out which culture is better and I want to make everything the best way but that’s a lot harder than just looking at them, I dunno how much I can even change my own culture

I think that’s pretty common though I don’t think most people stay in it

>>100531
yeah that’s why I’d get frustrated. it’s good you can be patient and all. are you taking cultures classes this semester?

>>100533
it means WOKE!!!!!! run booj or she’ll feminize you with her pansy liberalism!!!!!

>>100536
#hug can you hydrate and eat well and exercise a lil and have a sleep schedule and and and and to cope better with it maybe?

: ) I’ve had green tea toast

today

breath manually a lil and relax a lil maybe

I’m in the same boat at the same age with the same kinds of projects mostly :/

still in College at 25 🥲

>>100546
cool!! ^^ I hope you do too!

>>100550
yeah same about parents.
fr! I’m scared but excited to have a job and my own living space.

>>100547
oooh ahhhh

>>100556
heard that : )

that’s not unemployed silly!

underemployed

>>100563
whoah

you should look into clubs or something saddy! you can do a running club or painting club or smth and feel good and maybe have friends. nah ur not fuck it you’re at the same life stage and need homies

being a misanthrope is good actually

>>100560
but that’s tough and I hope things get better. I tried going to the library to work and exercising more and stuff and it didn’t make me productive. my bestie said I just need a job and supervision to help me build up work ethic and I think that may be true. if there is a better way to get those things done I’d love to hear it, and I’d be really happy if you do change your life in some way that it happens more.

misanthropes see everyone as equally bad and therefor they are radically equitable and charitble to all peoples

>>100583
this inage cant hurt me if i refuse to read it.

china should own everything in the world,thank you, please come again.

>>100590
hello

^-^

>>100595
taiwan is china and any chinese doesnt deserve the indignity of american friendship

>>100578
cool!

>>100599
yes

.play [YouTube]

china is not perfect in the same way that a ball bearing is not a platonic solid of a sphere, it's the closest approximate which we can create with reasonable effort, and expecting anything more is being greedy and praying for a level of perfection which does not increase practical usefulness

>>100586
I think it would be great too! crap there must be some internship or some crap you could do though where you can have supervision now : (

I wish I could get more in my work, I volunteer in a lab but it’s all in my own time on the computer, and I’ve done and aweful job so far

>>100606
yeah, kinda,,

thats cool ! drugs are bad

everytime i drink lots of alcohol vodka and beer i love china even more and i want to advance the position of the chinese peoples at the expense of anything else in the world.

>>100621
okay, im not offended by this, i think hawaii and guam should be independant too, this doesnt affect the strength of the peoples republic of china, it is just aesthetics, an inherently fascistic interest which a gigachad communist will not concern herself with

>>100617
in the scheme of things, it will maybe make it easier in the long run,

not sure what your dads startup is like though

>>100599
real about the life events but not really any dysphoria for me

>>100628
oh i think that will help then, even if its annoying

>>100623
The fbi will try to kill me because i am american born citizen of 3 generations

before that my entire family died of white lung at age 30 or younger. this will tell you exactly where i am from.

>>100606
I think so and drinking is scary anywayyyy

.play [YouTube]

>>100638
this but alcohol and loving chairman mao

>>100616
lol!

>>100639
also no job

>>100640
no they should be their own country

Better yet, they are rightful clay of people's republic of china as is all soil on earth

>>100617
I’m always doing chores or some stupid crap to waste my time and not focus on this stuff. I’m sure that stuff pulled you apart too : (

there should be a state called us territories and its every us territory

There should be a state named china and nothing else.

china is good because it is strong and usa is weak

>>100652
i think they do that environmental exploitation to support the first world

>>100652
only because they have been terribly exploited by american and global capitalists who exploit everyone, but they have turned their situation to their benefit through benevolent glory of chairman mao

>>100628
cool!

>>100658
china millitary will win against usa millitary any day of the week

>>100633
#hug

>>100662
usa will never take on a cause like that because it doesnt involve killing impovrished people for oil

>>100651
that’s seriously good you do that. I’ve tried to make time for things over break and gotten through like 1 page a day of a textbook, which disappoints me but I think i just need to keep at that and try to fix my other problems

what happens if ur trans and you get drafted? do they force you to detransition or would you be able to get out of it

>>100671
I look the millitary recruiter dead in the eyes and i tell him if i am given a gun i will immediate make bad things happen and it will be a very bad idea

>>100656
#kiss Lori ^^

>>100673
no, its falling apart sitting in warehouses because we dont spend any money on maintainance its extremely mismanaged and never used or monitored, we invented the best plane in the world and it only costs like 150,000 usd and we phased them out for a worse plane that costs like 50 million per plane and cant even kill a ptank

>>100675
yikes

that seems like something that shouldn't be a problem in 2025, :c

>>100673
yeah russia is aweful and I’m really glad saddy got opportunities

You can put all the fancy radar shit and whatever on an airplane, you can put all the missiles and shit you want inside of it, it will never beat the power of a large flying 50bmg turret

it was already figured out and we abandoned it because OLD REEE even though its already the platonic ideal of air to ground warfare